Medical Problems Of Kidney Transplantation

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Calcineurin inhibitors Calcineurin inhibitors are considered the principle factor answerable for progressive graft dysfunction by many investigators. There is little question that these agents are nephrotoxic and might result in the event of persistent nephropathy. Some investigators discovered that chronic interstitial fibrosis was more frequent in patients handled with cyclosporine than in these treated with tacrolimus (Nankivell et al., 2004). In one examine, kidney and pancreas transplant recipients treated with CNI were followed for 10 years...